Skip to content
Basenji Forums
  1. Home
  2. Basenji Health Issues & Questions
  3. If sib is "clear" do I need to test brother?

If sib is "clear" do I need to test brother?

Basenji Health Issues & Questions
  • E

    Then where does the "indeterminate" result come from?

    0
  • lvossL

    The "interdeterminate" result comes when a dog has inherited an incomplete set of markers. When this happens there is no way to know whether they have the inherited the gene with the partial set of markers or not so they are labeled "indeterminate".

    0
  • J

    im still confused, how can you have indeterminate between clear and carrier but not between carrier and affected and why does a lot of family members come back as indeterminate between clear and carrieri could understand if it was only one or two but it is most of them

    0
  • E

    Since this is just a marker test, "Indeterminate" results mean that some of the markers are found, and some are not. So the gene could be present, or not present. Indeterminate actually could be affected, carrier or clear, it is just not possible to tell, because the markers are incomplete.

    Marker testing is a little trickier than direct testing. It is good, but there are holes in the test, since the genes and markers aren't totally "fixed" in their positions on the genome. Markers and the genes they are used to track can become separated by mutations.

    0
  • lvossL

    @jules:

    im still confused, how can you have indeterminate between clear and carrier but not between carrier and affected and why does a lot of family members come back as indeterminate between clear and carrieri could understand if it was only one or two but it is most of them

    I was at the 2007 Nationals and asked about this and they said that they just haven't seen any Indeterminate between Carrier and Affected at that time. I find that hard to believe also but the lab is sticking to that explanation.

    As far as some families have lots of IND, an IND has 1 set of markers for Clear and one IND set so when bred according to the guidelines they will produce either Clear or IND offspring. It also seems that in some families that area is more prone to changes so high rates of IND occur. The lab is working to zero in on the gene so all of the IND results can be resolved.

    0
  • J

    well i know of one family that produced affected and IND in the same litter that was why i was asking i will be glad when the gene is found then we can all be sure

    0
  • lvossL

    A carrier can produce, Carriers, Affecteds, Clears, and IND depending on who they are bred to.

    0
  • J

    what about a carrier to an IND

    0
  • lvossL

    I have seen them produce Affected but those dogs really should be Indeterminate between Carrier and Clear but the lab never responded about that.

    The possible outcomes should be Clear, Carrier, IND, Indeterminate between Carrier and Affected based on the explanation the lab has given us.

    0
  • J

    i have seen ind and affected in the same litter

    0

Suggested Topics

  • tanzaT

    Fanconi re-testing (Linkage test, now Direct Gene Test)

    Basenji Health Issues & Questions
    25
    0 Votes
    25 Posts
    11k Views
    BettawhippetB
    That is a huge relief about the cheek swab…She absolutely HATED having her blood drawn and has been mistrustful of the vet and vet techs ever since. I didn't not realize that there were many errors in the original test. I stopped frequenting this forum shortly after I had her test done and haven't really heard anything from the basenji world until I got the e-mail. I will definitely get this re-test done as soon as possible and will pick up some strips tomorrow so I can start testing her urine. Thankfully she has not been showing any signs of poor health and has always done well on checkups.
  • K

    Need Advise anv Vet wants over $1000 for tests

    Basenji Health Issues & Questions
    19
    0 Votes
    19 Posts
    5k Views
    DebraDownSouthD
    @YodelDogs: I cannot even begin to fathom any normal diagnostic tests that would cost $1,000? A senior profile at my vet clinic includes a physical exam, complete blood panel, urinalysis, and fecal exam is is only about $100. LOL give me your vet's name. At my vet it's nearly 200. I'll drive to Atlanta! To the OP, yes get urine tested for infection first. Bladder/kidney could cause lots of pain walking and picking up. Start simple. Also, on the weight….I know folks here get tired of my saying it, but... first treat for worms even if none show up in fecal. DO NOT USE OTC, get from vet. Then, order cyproheptidine. It is a cheap antihistamine that works miracles with increasing appetite. My basenji was getting to the bone stage, massive testing... all normal. She simply didn't care if she ate. No matter what your vet says, you don't go by AMOUNT for what is right, you go by results. If they eat and are thin, they need MORE FOOD or food with higher calories. Also, you might try something like FASTRACK, healthy bacteria which helps them USE the food they eat much better.
  • DebraDownSouthD

    Fanconi in pups of "clear" parents?

    Basenji Health Issues & Questions
    43
    0 Votes
    43 Posts
    25k Views
    SalisS
    @JoT: Salis, Please contact Liz Hansen at the research lab and inform her of this situation. She will need the full names of your dog and both parents. Please send her an email at : HansenL@missouri.edu, Liz is very nice and quite helpful. She will help you understand the results. She will investigate your test. JoT, thank you! I've already wrote Liz Hansen:-) I'm a bit unlucky with it test, i made order in January and after half a year I got this result! Lucky it's not affected!
  • KitKatK

    When to test

    Basenji Health Issues & Questions
    6
    0 Votes
    6 Posts
    2k Views
    khanisK
    And chances are that your vet will tell you that there is no test. Just because it has been available for nearly two years does not mean that they know it is now here. You can do the fanconi tests without seeing a vet at all. Finger's crossed both your Bs come back NOT affected.
  • AndrewA

    Update on Booger's "allergies"

    Basenji Health Issues & Questions
    19
    0 Votes
    19 Posts
    4k Views
    AndrewA
    @tanza: Not to put any pressure on you or the Vet.. but to me… blood work is one of the most important tools.... and I am surprised that at least even with an appointment next week ... that they didn't take blood while he was there.... If it was me... and I am a "freak" about doing blood panels.. I would have insisted on at least that..... Thanks for letting me know. As Booger & Lola are my first "grown up" dogs (my parents took care of sick dogs growing up & we never had many issues until 1 got cancer), I really honestly don't know all the things I should be looking for or asking about. I will definitely call & ask about that. Booger does seem a LOT better today than he did yesterday, which is good. I don't take this as much of a sign of anything, but it at least makes me feel better knowing he isn't so miserable. He's a lot perkier & more playful. He gave us some playful baroos earlier, too, which is a rare treat!
  • gbroxonG

    Tell me…What's Your Opinion of "Hybrid Vigor"?

    Basenji Health Issues & Questions
    25
    0 Votes
    25 Posts
    13k Views
    RockysWomanR
    Speaking of "desinger" breeds… my dh (for the longest time!) was trying to convince me to breed our Papillion to a mini daschund. All I could picture was huge ears that may or may not flip up at a moments notice, a super long body, and long legs. It would look like something out of a Salvidor Dali picture!!! EEk!